Listen to the newest episode of AAHKS Amplified with host William B. Kurtz, MD talking to Michael E. Neufeld, MD, MSc, FRCSC about his award-winning study on Synovial Metal Ions, which compared intraarticular synovial fluid levels of metal ions in patients who underwent cemented primary TKA with a hypoallergenic implant vs. a matched cohort of standard cobalt-chromium (Co-Cr) containing implants at a minimum two-year follow-up. Interestingly, the study found that patients with hypoallergenic implants had intraarticular synovial Ni ion levels 3.6 times higher vs. standard implant controls, contesting the use of this hypoallergenic implant for Ni allergy/hypersensitivity. The research, “Nickel Free” vs. Standard Cobalt-Chrome Containing Total Knee Replacement,” received the James A. Rand, MD, Young Investigator’s Award at the 2025 AAHKS Annual Meeting.  

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